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I have severe bone pain in my legs and frequent bowel movements up to fifteen times per day. parathyroid scan showed nothing abnormal. after taking methotrexate only three days i saw marked improvement. after 28 day trial, pain in the legs is 80% improved, (am a multiply operated spine patient so did not expect 100%). bowel movements are more normal and once per day as they should be. this shows with just one month of treatment, that i do have parathyroid disease that was not picked up on scans. now i can pursue treatment through surgery.
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